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Genital Herpes Infection, Serologic Screening, 2016

* Indicates an old grade definition

Recommendations: Serologic Screening for Genital Herpes Infection

Clinical Consideration:

Patient Population Under Consideration

This recommendation statement applies to asymptomatic adolescents and adults, including those who are pregnant, without a history of genital HSV infection.

Screening Tests

The USPSTF does not recommend serologic screening for genital HSV infection in asymptomatic persons.


The CDC provides guidance for the diagnosis and management of genital HSV infection.2

Additional Approaches to Prevention

The USPSTF recommends intensive behavioral counseling interventions to reduce the likelihood of acquiring an STI for all sexually active adolescents and for adults at increased risk.3

Useful Resources

The USPSTF has issued recommendations on screening for other STIs, including chlamydia and gonorrhea,4 hepatitis B virus,5 human immunodeficiency virus (HIV),6 and syphilis.7

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