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Thyroid Dysfunction, Screening, 2015

* Indicates an old grade definition

Recommendations: Screening for Thyroid Dysfunction

  • Thyroid Dysfunction: Screening -- Nonpregnant, Asymptomatic Adults
    Grade: I
    Specific Recommendations:

    The USPSTF concludes that the current evidence is insufficient to assess the balance of benefits and harms of screening for thyroid dysfunction in nonpregnant, asymptomatic adults.

    Frequency of Service:

    The optimal screening interval for thyroid dysfunction (if one exists) is unknown.

    Risk Factor Information:

    The most common cause of hypothyroidism in the United States is chronic autoimmune (Hashimoto) thyroiditis. Risk factors for an elevated TSH level include female sex, advancing age, white race, type 1 diabetes, Down syndrome, family history of thyroid disease, goiter, previous hyperthyroidism (possibly due in part to ablation therapy leading to iatrogenic thyroid dysfunction), and external-beam radiation in the head and neck area.

    Common causes of hyperthyroidism include Graves disease, Hashimoto thyroiditis, and functional thyroid nodules. Risk factors for a low TSH level include female sex; advancing age; black race; low iodine intake; personal or family history of thyroid disease; and ingestion of iodine-containing drugs, such as amiodarone.

    The USPSTF found no direct evidence that treatment of thyroid dysfunction based on risk level alters final health outcomes.

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